Dr. Mario Online Rx

Dr. Mario Online Rx is a remake of the classic Dr. Mario puzzler. You can make your Mii appear in place of the Mario characters, and can challenge friends over Wi-Fi. The game includes the Saikin Bokumetsu game from the Japanese Brain Age 2, which can now be play cooperatively with four players.

Looks dope. I was a huge fan of Dr. Mario back in the day.
The remake is definitely gonna rekindle good memories, lolz!